… the development of compound 48/80-induced light avoidance in male mice, we assessed …
in the compound 48/80-induced light aversion. Administration of 48/80 in Myd88 −/− mice …

… Compound 48/80-induced degranulation of mast cells in the dura mater in compound 48/80 …
Mast cell degranulation mediates compound 48/80-induced meningeal vasodilatation …

… released after mast cell degranulation in C57Bl/6J mice. … if compound 48/80 induced
contractions were mediated by … is involved in compound 48/80-induced 356 contractions, …

… of the CP48/80-mediated degranulation reaction by ATP was mediated by the P2X4R. First,
… /80-mediated degranulation was absent in PMCs from P2rx4 −/− mice. PMCs prepared from …

… mouse model and RT-qPCR, we investigated the effect on ssON on LL-37-induced inflammation.
We reveal that both mast cell degranulation … -37-mediated activation of skin mast cells, …

… production in compound 48/80-induced systemic anaphylactic … is caused by IgE-mediated
mast cell degranulation and IgE-… femurs and tibias from C57BL/6J mice (male, 8 weeks old), …

… mediated by immunoglobulin E (IgE-dependent). As the main response cells in allergic
diseases, mast cells (MCs) can degranulate to … (PCA) mouse model and in RBL-2H3 cells both in …

… mediated contractions rapidly desensitize, whereas the mast … (F): In urothelium-intact strips
from mast cell-sufficient mice, … no effect on compound 48/80-induced contractions. Results are …

… mast cell degranulation and, thus, increasing histamine release. Bromhexine mediates its
… bromhexine is able to alleviate C 48/80-induced acute itch in mice. According to our findings…

… It is sometimes difficult to detect drug-induced cutaneous reactions suggestive of drug
hypersensitivity in rats or mice. This is because rats or mice are tolerant to immune-mediated drug …